Fast Food Nation meets The Corrections in the brilliant literary debut T.C. Boyle calls “funny and moving.”

David Leveraux is an Apprentice Flavor Chemist at one of the world’s leading flavor production houses. While testing Sweetness #9, he notices that the artificial sweetener causes unsettling side-effects in laboratory rats and monkeys. But with his career and family at risk, David keeps his suspicions to himself.

Years later, Sweetness #9 is America’s most popular sweetener–and David’s family is changing. His wife is gaining weight, his daughter is depressed, and his son has stopped using verbs. Is Sweetness #9 to blame, along with David’s failure to stop it? Or are these just symptoms of the American condition?

On an icy winter night in an isolated house in rural Vermont, a seasoned midwife named Sibyl Danforth takes desperate measures to save a baby’s life. She performs an emergency cesarean section on a mother she believes has died of a stroke. But what if Sibyl’s patient wasn’t dead—and Sybil inadvertently killed her? As Sibyl faces the antagonism of the law, the hostility of traditional doctors, and the accusations of her own conscience, Midwives engages, moves, and transfixes us as only the very best novels ever do.

Ann Patchett (Bel Canto, The Magician’s Assistant) returns with a provocative novel of morality and miracles, science and sacrifice set in the Amazon rainforest–a gripping adventure story and a profound look at the difficult choices we make in the name of discovery and love.

In a narrative replete with poison arrows, devouring snakes, scientific miracles, and spiritual transformations, State of Wonder presents a world of stunning surprise and danger, rich in emotional resonance and moral complexity.